There are some crucial matches this week and some very hard ones to predict.
Who can predict which struggling side will come out on top in the south-east Queensland derby between Brisbane and the Gold Coast or at the top of the ladder, who's likely to win between Penrith and Souths?
It's time to get your tips in - enter them now to make sure you don't miss out.
If you need help on how each team is travelling, Jamie Soward's Power Rankings is the best place to go for an accurate gauge on who's travelling well and who's doing not so well.
Here are the NRL.com expert panel's predictions for the round.
Fox Sports reporter Hannah Hollis has lost the outright lead, joined in first place by the mysterious NRL Fantasy guru Lone Scout in the race to be this year's top tipster.
Just one tip behind them is Ladies Who League's Mary Konstantopoulos and Sharks premiership winner Michael Ennis.
According to our panel, there is only one match with a unanimous favourite with everyone predicting the Roosters to get the better of the Dragons on Friday.