The Dragons produced one of their best wins of the season last weekend in downing Newcastle 40-28 to sit in 10th place after a slow start to the season.
Wests Tigers sit in eighth place fom two wins from five matches after some inconsistent performances by Coach Todd Payten's men in recent weeks. They lost 24-14 to the Storm last Monday night.
"It is a crucial game for us as we dont want to have to rely on a run of wins to get us into the semi finals,'' Payten said.
"They have a very smart hooker in Craig Garvey, a big front rower in Kem Seru who has given us some grief in the past and a classy centre in Charly Runciman."
Kick-off is 12.45pm.