The match kicks off at 12.45pm. Penrith sit second on the ladder with Wests Tigers in fifth place.
With regular captain Kyle Lovett promoted to the Wests Tigers NSW Cup team alongside Brenden Santi, Payten has given the leadership role to five-eighth Matt Mulcahy.
Payten has moved full-back Kurtis Rowe to the wing with Delouise Hoeter the new full-back.
WESTS TIGERS NYC TEAM TO PLAY PENRITH