Captain Robbie Farah will return from a fractured knuckle in a huge boost for the Wests Tigers and will become the most capped player in the Clubs history.
Farah equalled the record, set at 201 games by Chris Heighington, in the Round 21 match against the Gold Coast Titans before leaving the field through injury.
Boom rookie Sauaso Sue will again spend this week on the sidelines after being ruled out of the Rabbitohs clash with a foot injury.
Coming off a 34-18 victory against the Dragons, Potter said that the return of Farah will be a huge boost coming up against the second-placed Rabbitohs.
Although Joel Luani has been doing a fantastic job over the past few weeks and getting better with each game, Robbie Farah will certainly help us.
"Robbie's leadership around the park is outstanding, especially considering we are fielding a young side so I am looking forward to having him back out there."
Farah will join Benji Marshall (200 NRL games) and Lote Tuqiri (150 NRL games) who will also bring up milestones in the clash at Allianz Stadium.
We have a couple of milestones, Tuqiri plays his 150th NRL game which is impressive considering he had a stint in Rugby Union, Potter said.
"With Robbie and Benji bringing up their milestones it will make for a great evening this Friday night and I hope Wests Tigers fans will come out and celebrate these."
NRL debutants Luke Brooks and Nathan Brown will return to the Under 20s this weekend after impressing in the Dragons match, with Potter grateful the pair were given a one game salary cap exemption from the NRL.
Both young players had a great game last week and we were fortunate to play them, Potter said.
"Brooks and Brown will go back down to Under 20s but we look forward to seeing more of them in 2014."
Stay tuned for the full team announcement on weststigers.com.au later this afternoon.
MATCH DAY INFORMATION: WESTS TIGERS V RABBITOHS
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